COVID-19 Reporting and Information • HEERF I, II & III

William R. Carroll

Dr. William R. Carroll

Name:

William R.  Carroll, Ph.D.

Title:

Associate Professor

Department:

Chemistry

Email Address:

wcarroll@tntech.edu

Phone:

(931) 372-6094

Office:

Lab Science Commons, Rm 3314

ABOUT

Professional Preparation:

  • Associate Professor, Department of Chemistry, Tennessee Technological, University, 2018-present
  • Assistant Professor, Department of Chemistry, Tennessee Technological University, 2013-2018
  • Postdoctoral Scholar, Chemistry and Chemical Engineering, California Institute of Technology, John D. Roberts, 2010-2013
  • PhD, Chemistry, University of South Carolina, Ken Shimizu, 2010
  • Bachelor of Science, Chemistry, Georgia Institute of Technology, 2005

Teaching Interests:

    • Organic Chemistry 1 and 2
    • Spectroscopic Identification of Organic Molecules
    • Environmental Organic Chemistry

Research Interests:
Physical Organic Chemistry

    • Find the shape of small molecules: Using Residual Dipolar Couplings (RDC) determined through Nuclear Magnetic Resonance (NMR) spectroscopy my group establishes the three-dimensional shape of molecules in solution. We also  advance this methodology improving its reliability and ease of use.
      Active projects
      • Estimating error in structure assignments
      • Developing new orienting media based on 3D printed polymers
         
    • Improve how we run chemical reactions: The technology used to make molecules continues to improve and provide new opportunities. 
      Active projects
      • Application of improved reaction mixing and control in flow reactors to nanoparticle synthesis
      • Rapid optimization of reactions using design of experiment (DOE) for reduced environmental impact
      • Reaction monitoring via NMR in non-deuterated solvents
         
    • Use how molecules recognize each other: Applying our analytical measurements of molecular shape in solution to better understand, design, and encourage specific molecular interactions.
      Active projects
      • Pharmaceutical candidate synthesis
      • Examining protein-protein interactions (in collaboration with Dr. Xuanzhi Zhan)

Methods:

    • Synthesis using batch and flow reactors
    • Nuclear Magnetic Resonance (NMR) spectroscopy
    • Scanning Electron Microscopy (SEM)